cobicistat will improve the amount or result of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Treatment method triggers peripheral neuropathy (predominantly sensory); nevertheless, conditions of critical sensory and motor peripheral neuropathy have already been reported
To avoid dehydration, it is important to consume a lot of fluids if you are staying treated with this particular drug. Talk to your doctor or pharmacist Should you have any concerns.
Check Intently (one)triclabendazole will enhance the level or result of bortezomib by impacting hepatic enzyme CYP2C19 metabolism.
eslicarbazepine acetate will minimize the extent or result of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
stiripentol will increase the stage or effect of bortezomib by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Observe Carefully. Think about reducing the dose of CYP2C19 substrates, if adverse reactions are professional when administered concomitantly with stiripentol.
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tecovirimat will increase the level or effect of bortezomib by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor. Tecovirimat can be a weak inhibitor of CYP2C8 and CYP2C19. Keep an eye on for adverse results if coadministered with sensitive substrates of such enzymes.
bortezomib will improve the degree or effect of ruxolitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Not known.
indinavir will improve the level or influence of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Watch Carefully (one)lenacapavir will improve the stage or result of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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mitotane decreases amounts of bortezomib Anisperimus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Mitotane is a solid inducer of cytochrome P-4503A4; Thromboxane B2 check when coadministered with CYP3A4 substrates for feasible dosage changes.
Indicated for therapy of clients with mantle cell lymphoma as initially-line in previously untreated clients or anyone who has relapsed